Nasal chondromesenchymal hamartoma: an update

J Laryngol Otol. 2022 Dec;136(12):1140-1147. doi: 10.1017/S0022215121002267. Epub 2021 Aug 23.


Objective: Nasal chondromesenchymal hamartoma is a rare pathology that can present with a myriad of symptoms to ENT, maxillofacial and ophthalmology departments. This study reviewed the literature on nasal chondromesenchymal hamartoma as well as adding three new cases to the reported literature.

Method: This study was an up-to-date review of the world literature with the addition of three new cases to provide the most comprehensive review to date.

Results: A total of 56 patients with nasal chondromesenchymal hamartoma were identified, ranging from children to adults. Nasal symptoms and ocular symptoms were most common, and surgical resection was the most frequent treatment modality.

Conclusion: This study advocates for increased awareness of the condition associations for nasal chondromesenchymal hamartoma, multi-specialty treatment and the role for the ENT surgeon in treatment of the condition.

Keywords: Endoscopy; Otolaryngology; Paranasal Sinuses.

Publication types

  • Review

MeSH terms

  • Adult
  • Child
  • Diagnosis, Differential
  • Face
  • Hamartoma* / diagnosis
  • Hamartoma* / surgery
  • Humans
  • Medicine*
  • Surgeons*