Gaps in the diagnosis and management of iron overload in sickle cell disease: a 'real-world' report from the GRNDaD registry

Br J Haematol. 2021 Dec;195(5):e157-e160. doi: 10.1111/bjh.17762. Epub 2021 Aug 22.

Samuel R Wilson^{1

2

3}, Matthew Sears^{4

5}, Elizabeth Williams⁵, Jesse Drapekin^{6

7}, Ishwarya Sivakumar⁵, Susan Padrino⁶, Payal C Desai⁸, Ward Hager⁹, Deepa Manwani¹⁰, Leila J Clay¹¹, Joshua J Field¹², Julie Kanter¹³, Alice J Cohen¹⁴, Sana Saif Ur Rehman¹⁵, Sophie Lanzkron⁵, Jane A Little^{1

3}; GRNDaD investigators

¹ Department of Medicine, Division of Hematology, University of North Carolina, Chapel Hill, NC, USA.
² Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of North Carolina, Chapel Hill, NC, USA.
³ UNC Blood Research Center, University of North Carolina, Chapel Hill, NC, USA.
⁴ Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
⁵ Department of Medicine, Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
⁶ School of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
⁷ Department of Medicine, The University of Chicago Medical Center, Chicago, IL, USA.
⁸ Department of Hematology, The Ohio State University, Columbus, OH, USA.
⁹ Department of Pediatrics, UCSF Benioff Children's Hospital, Oakland, CA, USA.
¹⁰ Division of Pediatric Hematology, Oncology, Marrow and Blood Cell Transplantation, Albert Einstein College of Medicine, Bronx, NY, USA.
¹¹ Division of Hematology, Johns Hopkins All Children's Hospital, Johns Hopkins University School of Medicine, St. Petersburg, FL, USA.
¹² Blood Center of Wisconsin, Medical College of Wisconsin, Milwaukee, WI, USA.
¹³ Division of Hematology and Oncology, University of Alabama Birmingham, Birmingham, AL, USA.
¹⁴ Newark Beth Israel Medical Center, Newark, NJ, USA.
¹⁵ Department of Medicine, Division of Hematology, Washington University School of Medicine, St. Louis, MO, USA.

No abstract available

Keywords: Sickle cell disease; chronic transfusion; iron chelation; liver iron concentration; serum ferritin.

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