Background: Idiopathic intracranial hypertension (IIH) is a disease that can result in blindness if there is a delay in diagnosis. Although it is stated that cranial imaging should be normal among the diagnostic criteria, we know that some radiological parameters can be used for the pre-diagnosis of IIH.
Purpose: To determine the predictive value of radiological parameters for the diagnosis of IIH with cranial magnetic resonance imaging (MRI).
Material and methods: The study included a group of 19 patients with IIH ("IIH Group"), a group of 34 patients with hyperintensity around the optic nerve in cranial MRI ("Radiological Increased Intracranial Pressure Group"), and a "Control Group" consisting of 45 healthy individuals. All patients were evaluated using cranial MRI with respect to the presence/absence of empty sella, flattening of the posterior globe, hyperintensity around the optic nerve, optic nerve tortuosity, and optic nerve protrusion. In addition, optic nerve sheath diameter measurement was performed in all patients using cranial axial T2 sequence.
Results: It was found that optic nerve tortuosity (P = 0.002), flattening of the posterior globe (P = 0.013), and optic nerve protrusion (P = 0.033) were the best parameters to distinguish patients with IIH and those with optic nerve subarachnoid space enlargement. A scoring system was developed according to these data.
Conclusion: In the presence of hyperintensity around the optic nerve, it may be possible to evaluate optic nerve tortuosity, flattening of the posterior globe, and optic nerve protrusion using cranial MRI in order to come upon a preliminary diagnosis of IIH.
Keywords: Idiopathic intracranial hypertension; cranial MRI; intracranial pressure; optic nerve sheath diameter.