Anti-discoloration system: a new chlorhexidine mouthwash

J Biol Regul Homeost Agents. 2021 Jul-Aug;35(4 Suppl. 1):113-118. doi: 10.23812/21-4supp1-10.

Abstract

Chlorhexidine is defined as biocompatible, which is why it is used as a mouthrinse for the patient before starting dental procedures (2). It has the ability to bind well to teeth and mucous membranes and is released for twelve hours, which is why it is used as a treatment for gingivitis and also in post-operative wound healing. The long-term side effects of chlorhexidine are pigmentations. To remedy this, various types of antidiscoloration have been tried out over time. Nowadays there are other types of anti-discoloration systems such as, for example, in our study we used a test group containing an anti-discoloration system called SPPD. A single-center, prospective, double-blind randomized clinical trial on 84 patients. The investigated treatments consisted of 4 mouthwashes (CHX 0.12% SPDD alcohol free; CHX 0.20% SPDD alcohol free; CHX 0.12% alcohol free with ADS; CHX 0.20% alcohol free with ADS). Despite the limitations of the study, all the mouthwashes tested showed good efficacy in reducing the amount of plaque. Comparing the two experimental concentrations (0.12% and 0.20%) tested here demonstrates that the 0.20% chlorhexidine concentration slightly surpasses its 0.12% equivalent with regard to the PI and BI parameters. The SPDD is an innovative anti-discoloration system and gives the mouthwash a great taste.

Keywords: Chlorhexidine; discoloration; hydrogen peroxide; mouthwash; plaque; povidone iodine together.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Anti-Infective Agents, Local*
  • Chlorhexidine
  • Humans
  • Mouthwashes
  • Prospective Studies
  • Tooth Discoloration* / drug therapy

Substances

  • Anti-Infective Agents, Local
  • Mouthwashes
  • Chlorhexidine