Rapid removal of chloramphenicol via the synergy of Geobacter and metal oxide nanoparticles

Leilei Xiao; Fanghua Liu; P Senthil Kumar; Yunwei Wei; Jian Liu; Dianfeng Han; Shangjie Shan; Xingyu Wang; Run Dang; Jiafeng Yu

doi:10.1016/j.chemosphere.2021.131943

Rapid removal of chloramphenicol via the synergy of Geobacter and metal oxide nanoparticles

Chemosphere. 2022 Jan;286(Pt 3):131943. doi: 10.1016/j.chemosphere.2021.131943. Epub 2021 Aug 20.

Authors

Leilei Xiao¹, Fanghua Liu², P Senthil Kumar³, Yunwei Wei⁴, Jian Liu⁵, Dianfeng Han⁶, Shangjie Shan⁷, Xingyu Wang⁸, Run Dang⁹, Jiafeng Yu¹⁰

Affiliations

¹ CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, China; Key Laboratory of Coastal Biology and Biological Resources Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, PR China. Electronic address: llxiao@yic.ac.cn.
² CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, China; Key Laboratory of Coastal Biology and Biological Resources Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, PR China. Electronic address: fhliu@yic.ac.cn.
³ Department of Chemical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Chennai, 603110, India. Electronic address: senthilkumarp@ssn.edu.in.
⁴ Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou, 253023, PR China. Electronic address: sdweiyunwei@163.com.
⁵ Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou, 253023, PR China. Electronic address: liujian.cn@live.com.
⁶ Shandong Marine Resource and Environment Research Institute, Yantai, 264006, PR China. Electronic address: yantgongz@126.com.
⁷ Yantai University, Yantai, 264005, PR China. Electronic address: ssjnb15866145316@163.com.
⁸ Yantai University, Yantai, 264005, PR China. Electronic address: lmy1500446388@163.com.
⁹ Yantai University, Yantai, 264005, PR China. Electronic address: xiaodang2333@163.com.
¹⁰ Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou, 253023, PR China. Electronic address: jfyu1979@126.com.

PMID: 34426266
DOI: 10.1016/j.chemosphere.2021.131943

Abstract

The wide use of chloramphenicol and its residues in the environments are an increasing threat to human beings. Electroactive microorganisms were proven with the ability of biodegradation of chloramphenicol, but the removal rate and efficiency need to be improved. In this study, a model electricigens, Geobacter metallireducens, was supplied with and Fe₃O₄ and MnO₂ nanoparticles. Five times higher chloramphenicol removal rate (0.71 d^-1) and two times higher chloramphenicol removal efficiency (100%) was achieved. Fe₃O₄ and MnO₂ nanoparticles highly increased the current density and NADH-quinone oxidoreductase expression. Fe₃O₄ nanoparticles enhanced the expression of alcohol dehydrogenase and c-type cytochrome, while MnO₂ nanoparticles increased the transcription of pyruvate dehydrogenase and Type IV pili assembly genes. Chloramphenicol was reduced to a type of dichlorination reducing product named CPD3 which is a benzene ring containing compound. Collectively, Fe₃O₄ and MnO₂ nanoparticles increased the chloramphenicol removal capacity in MFCs by enhancing electron transfer efficiency. This study provides new enhancing strategies for the bioremediation of chloramphenicol in the environments.

Keywords: Antibiotic; Dechlorination; Electron transfer; Fe(3)O(4); MnO(2); Nanoparticles.

MeSH terms

Chloramphenicol
Geobacter* / genetics
Humans
Manganese Compounds
Metal Nanoparticles*
Oxidation-Reduction
Oxides

Substances

Manganese Compounds
Oxides
Chloramphenicol

Supplementary concepts

Geobacter metallireducens