Metastatic Breast Lobular Carcinoma to Unusual Sites: A Report of Three Cases and Review of Literature

Hossameldin Abdallah; Amira Elwy; Aya Alsayed; Ahmed Rabea; Nesreen Magdy

doi:10.14740/jmc3538

Metastatic Breast Lobular Carcinoma to Unusual Sites: A Report of Three Cases and Review of Literature

J Med Cases. 2020 Sep;11(9):292-295. doi: 10.14740/jmc3538. Epub 2020 Aug 6.

Authors

Hossameldin Abdallah¹, Amira Elwy^{2

3}, Aya Alsayed⁴, Ahmed Rabea¹, Nesreen Magdy³

Affiliations

¹ Medical Oncology Department, Shefaa Al-Orman Hospital, Luxor, Egypt.
² Pathology Department, South Egypt Cancer Institute, Assiut University, Assiut Governorate, Egypt.
³ Pathology Department, Shefaa Al-Orman Hospital, Luxor, Egypt.
⁴ Medical Oncology Department, National Cancer Institute, Cairo University, Egypt.

Abstract

Invasive lobular carcinoma of the breast is the second most common type of invasive breast carcinoma. Invasive lobular carcinoma has an unusual pattern of metastases, which poses a diagnostic challenge for both clinicians and pathologists. We herein present three cases of breast invasive lobular carcinoma presented with metastasis to unusual sites, namely, uterus, colon and stomach. We recommend a higher index of suspicion in any case with breast cancer developing gastrointestinal tract or genital tract symptoms.

Keywords: E- cadherin; GI metastases; Lobular carcinoma; Poorly cohesive carcinoma; Uterine bleeding.

Publication types

Case Reports