Recent Advances Towards Point-Of-Care Applications of Surface-Enhanced Raman Scattering Sensing

Front Chem. 2021 Aug 9:9:714113. doi: 10.3389/fchem.2021.714113. eCollection 2021.

Abstract

The ability to accurately diagnose at the point of care is crucial in many pathologies. However, current standard diagnostic practices can only be performed in specialized health or laboratory settings. To move diagnostic methods from a specialized lab to the point of care many alternate methods have been developed and proposed. Among them surface-enhanced Raman scattering (SERS) sensing offers advantageous features, such as simultaneous detection of multiple biotargets and increased accuracy. Many groups have been working towards the translation of SERS sensing methods from the lab to the point of need. In this mini review, we discuss interesting and recent developments in this effort, focusing on how different sensing mechanism can be used in point-of-care testing applications of SERS.

Keywords: diagnostics; microRNA (miRNA); plasmonics; point-of-care (POC); surface-enhanced Raman scattering (SERS).

Publication types

  • Review