Health-Promoting of Polysaccharides Extracted from Ganoderma lucidum

Nutrients. 2021 Aug 7;13(8):2725. doi: 10.3390/nu13082725.


Medicinal mushrooms are rich sources of pharmacologically active compounds. One of the mushrooms commonly used in traditional Chinese medicine is Ganoderma lucidum (Leyss. Ex Fr.) Karst. In Asian countries it is treated as a nutraceutical, whose regular consumption provides vitality and improves health. Ganoderma lucidum is an important source of biologically active compounds. The pharmacologically active fraction of polysaccharides has antioxidant, immunomodulatory, antineurodegenerative and antidiabetic activities. In this review, we summarize the activity of Ganoderma lucidum polysaccharides (GLP).

Keywords: Ganoderma lucidum; antidiabetic; antineurodegeneration; antioxidation; health-promoting properties; immunomodulation; natural medicines; phytochemicals.

Publication types

  • Review

MeSH terms

  • Antioxidants / pharmacology
  • Dietary Supplements / parasitology*
  • Humans
  • Hypoglycemic Agents / pharmacology
  • Immunologic Factors / pharmacology
  • Medicine, Chinese Traditional / methods*
  • Neuroprotective Agents / pharmacology
  • Polysaccharides / pharmacology*
  • Reishi / chemistry*


  • Antioxidants
  • Hypoglycemic Agents
  • Immunologic Factors
  • Neuroprotective Agents
  • Polysaccharides