Vertebroplasty as a palliative treatment option for intractable pain in pediatric patients with spinal tumors

Pediatr Blood Cancer. 2021 Dec;68(12):e29307. doi: 10.1002/pbc.29307. Epub 2021 Aug 27.

Abstract

Primary and secondary malignant tumors of the spine are relatively uncommon in the pediatric population but are associated with high morbidity and significantly decreased quality of life due to pain. Local management of these tumors is often challenging due to the importance of maintaining vertebral mechanical integrity as well as the spinal growth potential. Typically, surgery and/or radiation therapy have been used in the primary management of these tumors. However, treatment options become more limited when there is relapse or refractory disease, with re-resection or additional radiotherapy often not being viable therapies. Vertebroplasty is a currently underutilized modality that might provide significant pain palliation in cases of relapsed cancer in the spine.

Keywords: palliative care; pediatric cancer; rhabdomyosarcoma; spinal tumor; vertebroplasty.

MeSH terms

  • Central Nervous System Neoplasms* / complications
  • Child
  • Humans
  • Neoplasm Recurrence, Local
  • Pain, Intractable* / complications
  • Pain, Intractable* / therapy
  • Palliative Care
  • Quality of Life
  • Spinal Cord Neoplasms*
  • Spinal Neoplasms* / complications
  • Spinal Neoplasms* / radiotherapy
  • Spinal Neoplasms* / surgery
  • Treatment Outcome
  • Vertebroplasty*