Mapping of the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1

Ann Hum Genet. 1986 Jul;50(3):229-35. doi: 10.1111/j.1469-1809.1986.tb01043.x.

Abstract

The gene coding for the liver/bone/kidney isozyme of alkaline phosphatase, ALPL, has been mapped to human chromosome 1 using a monoclonal antibody TRA-2-54/2J and electrophoretic analysis to distinguish between the human and rodent isozymes in human/rodent somatic cell hybrids.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alkaline Phosphatase / analysis
  • Alkaline Phosphatase / genetics*
  • Animals
  • Cell Line
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 1*
  • Genes*
  • Humans
  • Hybrid Cells
  • Isoenzymes / analysis
  • Isoenzymes / genetics*
  • Mice
  • Radioimmunoassay
  • Rats

Substances

  • Isoenzymes
  • Alkaline Phosphatase