Lung Nodule Detection in CT Images Using Statistical and Shape-Based Features

J Imaging. 2020 Feb 24;6(2):6. doi: 10.3390/jimaging6020006.

Abstract

The lung tumor is among the most detrimental kinds of malignancy. It has a high occurrence rate and a high death rate, as it is frequently diagnosed at the later stages. Computed Tomography (CT) scans are broadly used to distinguish the disease; computer aided systems are being created to analyze the ailment at prior stages productively. In this paper, we present a fully automatic framework for nodule detection from CT images of lungs. A histogram of the grayscale CT image is computed to automatically isolate the lung locale from the foundation. The results are refined using morphological operators. The internal structures are then extracted from the parenchyma. A threshold-based technique is proposed to separate the candidate nodules from other structures, e.g., bronchioles and blood vessels. Different statistical and shape-based features are extracted for these nodule candidates to form nodule feature vectors which are classified using support vector machines. The proposed method is evaluated on a large lungs CT dataset collected from the Lung Image Database Consortium (LIDC). The proposed method achieved excellent results compared to similar existing methods; it achieves a sensitivity rate of 93.75%, which demonstrates its effectiveness.

Keywords: computed tomography (CT); computer-aided detection (CAD); lung cancer; nodule detection.