Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2021: Looking Forward as the Network Celebrates its 20th Year

Helen E Heslop; Edward A Stadtmauer; John E Levine; Karen K Ballen; Yi-Bin Chen; Amy E DeZern; Mary Eapen; Mehdi Hamadani; Betty K Hamilton; Parameswaran Hari; Richard J Jones; Brent R Logan; Leslie S Kean; Eric S Leifer; Frederick L Locke; Richard T Maziarz; Eneida R Nemecek; Marcelo Pasquini; Rachel Phelan; Marcie L Riches; Bronwen E Shaw; Mark C Walters; Amy Foley; Steven M Devine; Mary M Horowitz

doi:10.1016/j.jtct.2021.08.016

Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2021: Looking Forward as the Network Celebrates its 20th Year

Transplant Cell Ther. 2021 Nov;27(11):885-907. doi: 10.1016/j.jtct.2021.08.016. Epub 2021 Aug 27.

Authors

Helen E Heslop¹, Edward A Stadtmauer², John E Levine³, Karen K Ballen⁴, Yi-Bin Chen⁵, Amy E DeZern⁶, Mary Eapen⁷, Mehdi Hamadani⁷, Betty K Hamilton⁸, Parameswaran Hari⁷, Richard J Jones⁶, Brent R Logan⁷, Leslie S Kean⁹, Eric S Leifer¹⁰, Frederick L Locke¹¹, Richard T Maziarz¹², Eneida R Nemecek¹², Marcelo Pasquini⁷, Rachel Phelan⁷, Marcie L Riches¹³, Bronwen E Shaw⁷, Mark C Walters¹⁴, Amy Foley¹⁵, Steven M Devine¹⁵, Mary M Horowitz⁷

Affiliations

¹ Baylor College of Medicine, Houston, Texas. Electronic address: hheslop@bcm.edu.
² University of Pennsylvania, Philadelphia, Pennsylvania.
³ Icahn School of Medicine at Mount Sinai, New York, New York.
⁴ University of Virginia, Charlottesville, Virginia.
⁵ Massachusetts General Hospital, Boston, Massachusetts.
⁶ Johns Hopkins University, Baltimore, Maryland.
⁷ Center for International Blood & Marrow Transplant Research, Minneapolis, Minnesota.
⁸ Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.
⁹ Boston Children's Hospital, Boston, Massachusetts.
¹⁰ National Institutes of Health, Bethesda, Maryland.
¹¹ Moffitt Cancer Center & Research Institute, Tampa, Florida.
¹² Oregon Health & Science University, Portland, Oregon.
¹³ University of North Carolina, Durham, North Carolina.
¹⁴ University of California San Francisco, San Francisco, California.
¹⁵ National Marrow Donor Program, Minneapolis, Minnesota.

Abstract

In 2021 the BMT CTN held the 4th State of the Science Symposium where the deliberations of 11 committees concerning major topics pertinent to a particular disease, modality, or complication of transplant, as well as two committees to consider clinical trial design and inclusion, diversity, and access as cross-cutting themes were reviewed. This article summarizes the individual committee reports and their recommendations on the highest priority questions in hematopoietic stem cell transplant and cell therapy to address in multicenter trials.

Keywords: BMT; Cell Therapy; Clinical Trial.

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Bone Marrow Transplantation*
Clinical Trials as Topic
Hematopoietic Stem Cell Transplantation
Humans
Transplants*

Abstract

Publication types

MeSH terms

Grants and funding