Measuring vitamin C in critically ill patients: clinical importance and practical difficulties-Is it time for a surrogate marker?

Sander Rozemeijer; Frans A L van der Horst; Angélique M E de Man

doi:10.1186/s13054-021-03670-x

Measuring vitamin C in critically ill patients: clinical importance and practical difficulties-Is it time for a surrogate marker?

Crit Care. 2021 Aug 31;25(1):310. doi: 10.1186/s13054-021-03670-x.

Authors

Sander Rozemeijer¹, Frans A L van der Horst², Angélique M E de Man³

Affiliations

¹ Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. s.rozemeijer@amsterdamumc.nl.
² Department of Clinical Chemistry, Reinier Medical Diagnostic Center, Delft, The Netherlands.
³ Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2021. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2021 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from https://link.springer.com/bookseries/8901 .

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Ascorbic Acid / analysis*
Ascorbic Acid / blood
Biomarkers / analysis*
Biomarkers / blood
Critical Illness
Humans
Predictive Value of Tests
Treatment Outcome

Substances

Biomarkers
Ascorbic Acid