Red blood cell exchange transfusion may be beneficial and should be considered in the early management of patients with sickle cell disease and COVID-19 to prevent the need for intubation and intensive care unit admission due to respiratory distress.
Keywords: COVID‐19; acute chest syndrome; hereditary persistence of fetal hemoglobin; red blood cell exchange transfusion; sickle cell disease.
© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.