Genus Pseudonocardia: What we know about its biological properties, abilities and current application in biotechnology

J Appl Microbiol. 2022 Feb;132(2):890-906. doi: 10.1111/jam.15271. Epub 2021 Sep 15.

Abstract

The genus Pseudonocardia belongs to a group of Actinomycetes, and is a member of the family Pseudonocardiacea. The members of this genus are aerobic, Gram-positive, non-motile bacteria that are commonly found in soil, plant and environment. Although this genus has a low clinical significance; however, it has an important role in biotechnology due to the production of secondary metabolites, some of which have anti-bacterial, anti-fungal and anti-tumour effects. The use of phenotypic tests, such as gelatinase activity, starch hydrolysis, catalase and oxidase tests, as well as molecular methods, such as polymerase chain reaction, are necessary for Pseudonocardia identification at the genus and species levels.

Keywords: Pseudonocardia; Actinomycete; biotechnology; degradation; secondary metabolites.

Publication types

  • Review

MeSH terms

  • Actinomycetales* / genetics
  • Bacterial Typing Techniques
  • Base Composition
  • Biotechnology
  • DNA, Bacterial
  • Phylogeny
  • Pseudonocardia
  • RNA, Ribosomal, 16S
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial
  • RNA, Ribosomal, 16S