Long-term persistence of neutralizing SARS-CoV-2 antibodies in pets

Transbound Emerg Dis. 2022 Sep;69(5):3073-3076. doi: 10.1111/tbed.14308. Epub 2021 Sep 12.


We monitored the severe acute respiratory syndrome coronavirus 2 antibody response in seven dogs and two cats by using two multispecies ELISA tests, plaque reduction neutralisation test and virus neutralization. SARS-CoV-2 neutralizing antibodies in pets persisted up to 10 months since the first positive testing, thus replicating observations in COVID-19 human patients.

Keywords: ELISA; SARS-CoV-2 antibodies; cat; dog; long-term persistence; plaque reduction neutralization test; virus neutralization.

MeSH terms

  • Animals
  • Antibodies, Neutralizing
  • Antibodies, Viral
  • COVID-19* / veterinary
  • Dog Diseases*
  • Dogs
  • Humans
  • Neutralization Tests / veterinary
  • SARS-CoV-2


  • Antibodies, Neutralizing
  • Antibodies, Viral