Efficacy of the colchicine add-on therapy in patients with autoimmune chronic urticaria

Dermatol Ther. 2021 Nov;34(6):e15119. doi: 10.1111/dth.15119. Epub 2021 Sep 15.

Abstract

Chronic urticaria is in some cases very difficult to treat, we aimed to evaluate the effect of colchicine on chronic urticaria management. Fifty-five euthyroid patients with chronic urticaria were examined based on UQL and UAS7 questionnaires. The overall UQL-Q score after 3 months has not any statistical difference between groups. The overall UQL-Q score changes between groups was not statistically different. However, the UQL-Q score significantly reduces during study period in each group. In conclusion, colchicine can manage the sign and symptoms of chronic urticaria, which improve the patients' quality of life.

Keywords: anti-TPO; chronic urticaria; colchicine; management.

MeSH terms

  • Chronic Disease
  • Chronic Urticaria* / drug therapy
  • Colchicine / adverse effects
  • Humans
  • Quality of Life
  • Urticaria* / diagnosis
  • Urticaria* / drug therapy

Substances

  • Colchicine