Role of hyperbaric oxygen in glioma: a narrative review

Med Gas Res. 2022 Jan-Mar;12(1):1-5. doi: 10.4103/2045-9912.324589.

Abstract

Gliomas are common brain mass with a high mortality rate. Patients with gliomas have a severely bad outcome, with an average survive duration less 15 months because of high recurrent rate and being resistant to radio-therapy and chemistry drugs therapy. Hyperbaric oxygen is extensively taken as an adjuvant treatment for various disease conditions. To know the characteristics of hyperbaric oxygen as a remedy for gliomas, we find that, in general, hyperbaric oxygen shows an obviously positive effect on the treatment of gliomas, and it can also relieve the complications caused by postoperative radiotherapy and chemotherapy of gliomas. Whereas, several researches have shown that hyperbaric oxygen promotes glioma progression.

Keywords: HBO; adverse; complication; efficacy; glioma; hyperbaric oxygen; mechanism; treatment.

Publication types

  • Review

MeSH terms

  • Brain Neoplasms* / therapy
  • Combined Modality Therapy
  • Glioma* / therapy
  • Humans
  • Hyperbaric Oxygenation*
  • Oxygen

Substances

  • Oxygen