Clinical characteristics of immunoglobulin G4-positive interstitial pneumonia

Masamichi Komatsu; Hiroshi Yamamoto; Shoko Matsui; Yasuhiro Terasaki; Akira Hebisawa; Tae Iwasawa; Takeshi Johkoh; Tomohisa Baba; Atsushi Miyamoto; Tomohiro Handa; Keisuke Tomii; Yuko Waseda; Masashi Bando; Haruyuki Ishii; Yasunari Miyazaki; Akihiko Yoshizawa; Tamiko Takemura; Yoshinori Kawabata; Takashi Ogura

doi:10.1183/23120541.00317-2021

Clinical characteristics of immunoglobulin G₄-positive interstitial pneumonia

ERJ Open Res. 2021 Aug 31;7(3):00317-2021. doi: 10.1183/23120541.00317-2021. eCollection 2021 Jul.

Authors

Masamichi Komatsu¹, Hiroshi Yamamoto¹, Shoko Matsui², Yasuhiro Terasaki³, Akira Hebisawa⁴, Tae Iwasawa⁵, Takeshi Johkoh⁶, Tomohisa Baba⁷, Atsushi Miyamoto⁸, Tomohiro Handa⁹, Keisuke Tomii¹⁰, Yuko Waseda¹¹, Masashi Bando¹², Haruyuki Ishii¹³, Yasunari Miyazaki¹⁴, Akihiko Yoshizawa¹⁵, Tamiko Takemura¹⁶, Yoshinori Kawabata¹⁷, Takashi Ogura⁷

Affiliations

¹ First Dept of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
² Health Administration Center, University of Toyama, Toyama, Japan.
³ Dept of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan.
⁴ Division of Clinical Pathology, Asahi Central Hospital, Asahi, Japan.
⁵ Dept of Radiology, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
⁶ Dept of Radiology, Kansai Rosai Hospital, Amagasaki, Japan.
⁷ Division of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
⁸ Dept of Respiratory Medicine, Respiratory Center, Toranomon Hospital, Tokyo, Japan.
⁹ Dept of Advanced Medicine for Respiratory Failure, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
¹⁰ Dept of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
¹¹ Third Dept of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
¹² Division of Pulmonary Medicine, Dept of Medicine, Jichi Medical University, Tochigi, Japan.
¹³ Dept of Respiratory Medicine, Kyorin University School of Medicine, Tokyo, Japan.
¹⁴ Dept of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
¹⁵ Dept of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.
¹⁶ Dept of Pathology, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
¹⁷ Division of Diagnostic Pathology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan.

Abstract

This study suggests that IgG₄ ⁺ IP with abundant IgG₄ ⁺ cells and elevated serum IgG₄ levels could be treated differently from IgG₄-related respiratory disease due to potential differences in disease behaviour and response to corticosteroid therapy https://bit.ly/3dUo2cu.