[Intracerebral haemorrhage twelve days after vaccination with ChAdOx1 nCoV-19]

Ugeskr Laeger. 2021 Aug 30;183(35):V05210425.
[Article in Danish]


The COVID-19-pandemic has had a huge impact on health and economics all over the world resulting in widespread vaccine development. Vaccine-induced immune thrombotic thrombocytropenia has been described, suggesting a link between the two adeno-vector vaccines ChAdOx1 nCoV-19 (Vaxzevria from AstraZeneca) and Ad26.COV2-S (Janssen from Johnson and Johnson). This rare clinical condition should be suspected in patients with headache, abdominal pain, suspected thrombosis or hemorrhage and thrombocytopenia within 3-30-day post vaccine. In this case report a previously healthy man had thrombocytopenia with fatal intracerebral haemorrhage which was suspected to be related to vaccine.

Publication types

  • Case Reports

MeSH terms

  • COVID-19 Vaccines
  • COVID-19*
  • Cerebral Hemorrhage
  • ChAdOx1 nCoV-19
  • Humans
  • Male
  • SARS-CoV-2
  • Vaccination


  • COVID-19 Vaccines
  • ChAdOx1 nCoV-19