A Multilocus Blood-Based Assay Targeting Circulating Tumor DNA Methylation Enables Early Detection and Early Relapse Prediction of Colorectal Cancer

Gastroenterology. 2021 Dec;161(6):2053-2056.e2. doi: 10.1053/j.gastro.2021.08.054. Epub 2021 Sep 4.

¹ Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: gxcai@fudan.edu.cn.
² Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
³ Department of Gastroenterology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
⁴ Singlera Genomics (Shanghai) Ltd, Shanghai, China. Electronic address: rliu@singleragenomics.com.
⁵ Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China. Electronic address: lli@smu.edu.cn.
⁶ Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address: zhou.pinghong@zs-hospital.sh.cn.
⁷ Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
⁸ Singlera Genomics (Shanghai) Ltd, Shanghai, China.
⁹ Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
¹⁰ Department of Laboratory medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
¹¹ Department of Gastroenterology, Dalian University affiliated Xinhua Hospital, Dalian, China.
¹² Department of Gastroenterology, West China Hospital, Sichuan University, China.

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