Role of ivermectin in patients hospitalized with COVID-19: a systematic review of literature

Adv Respir Med. 2021;89(4):413-418. doi: 10.5603/ARM.a2021.0088.


The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected almost every country in the world since De-cember 2019. Despite the efforts of the human race to combat the virus, we are still looking for an evidence-based permanent cure for the disease. Ivermectin has recently emerged as one of the therapies having a beneficial effect on COVID-19. Ivermectin, owing to its properties, continues to be a possible treatment against the COVID-19 disease. Already being a mainstream drug with minimal adverse effects, it garners valid consideration. It's use in hospitalized patients, randomized controlled trials, and observational studies has also supported its implementation. In this article, we have reviewed recent studies and explored the effectiveness of ivermectin in hospitalized COVID-19 patients.

Keywords: COVID-19; SARS-CoV-2; ivermectin; therapy; treatment; virus.

Publication types

  • Systematic Review

MeSH terms

  • Antiviral Agents / adverse effects
  • Antiviral Agents / therapeutic use*
  • COVID-19 / drug therapy*
  • COVID-19 / therapy
  • Humans
  • Ivermectin / adverse effects
  • Ivermectin / therapeutic use*
  • Length of Stay / statistics & numerical data


  • Antiviral Agents
  • Ivermectin

Supplementary concepts

  • COVID-19 drug treatment