Managing cardiovascular risk in people living with HIV in Asia - where are we now?

Jun Yong Choi; Grace Chung Yan Lui; Chia-Te Liao; Chia-Jui Yang

doi:10.1111/hiv.13164

Managing cardiovascular risk in people living with HIV in Asia - where are we now?

HIV Med. 2022 Feb;23(2):111-120. doi: 10.1111/hiv.13164. Epub 2021 Sep 7.

Authors

Jun Yong Choi^{1

2}, Grace Chung Yan Lui³, Chia-Te Liao^{4

5

6}, Chia-Jui Yang^{7

8}

Affiliations

¹ Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
² AIDS Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
³ Department of Medicine and Therapeutics, Faculty of Medicine, Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
⁴ Division of Cardiology, Chi-Mei Medical Centre, Tainan, Taiwan.
⁵ Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁶ Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan, Taiwan.
⁷ School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
⁸ Division of Infectious Diseases, Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.

PMID: 34494350
DOI: 10.1111/hiv.13164

Abstract

As the life expectancy of people living with HIV (PLWH) approaches that of the general population, the burden of comorbidities such as cardiovascular disease (CVD) is increasing. Regardless of HIV status, about 50% of CVD deaths worldwide occur in Asia, and Asian PLWH have a high prevalence of conventional CVD risk factors, such as smoking, dyslipidaemia, hypertension and insulin resistance or diabetes. As well as conventional CVD risk factors, PLWH have HIV-specific risk factors such as chronic inflammation, immune activation and endothelial damage, as well as risk factors related to antiretroviral therapy. This review describes the current knowledge on the epidemiology and risk factors of CVD in Asian PLWH and provides an Asian perspective on the recommendations for managing CVD risk in PLWH.

Keywords: Asia; HIV; antiretroviral therapy; cardiovascular diseases; heart disease risk factors.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Cardiovascular Diseases* / epidemiology
Cardiovascular Diseases* / etiology
HIV Infections* / complications
HIV Infections* / drug therapy
HIV Infections* / epidemiology
Heart Disease Risk Factors
Humans
Life Expectancy
Risk Factors