Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion

doi:10.1056/NEJMc2113891

. 2021 Oct 14;385(16):1533-1535.

doi: 10.1056/NEJMc2113891. Epub 2021 Sep 8.

Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion

Collaborators, Affiliations

Collaborators

CDC v-safe Covid-19 Pregnancy Registry Team:
Amena Abbas, Amanda Akosa, Dayna S Alexander, Kathryn E Arnold, Jamal Bankhead, Tabatha Barber, Amy Blum, Ellen Boundy, Virginia B Bowen, Kailyn M Brooks, Cheryl Broussard, Tara Brown, Veronica K Burkel, Gyan Chandra, Karen Chang, Dena Cherry-Brown, Monica DiRienzo, Tuyen Do, Charise Fox, Julianne M Gee, Robbie Gray, Caitlin J Green, Jennifer Hamborsky, Anne M Hause, Jennifer Hegle, Obehi Ilenikhena, Jessly Joy, Ashley Judge, Alaya Koneru, Zanie Leroy, Birook Mekonnen, Anne Moorman, Pedro L Moro, John F Nahabedian 3rd, Morgan Nail, Andrea Neiman, Kimberly Newsome, Suzanne Newton, Keydra Phillips Oladapo, Nicole S Olgun, H Pamela Pagano, Lakshmi Panagiotakopoulos, Youngjoo Park, Corrine Parker, Kara Polen, Emmitt Rathore, Tom T Shimabukuro, Penelope Strid, Jennifer M Swanson, Ayzsa F Tannis, Naomi K Tepper, Letha Thomas, Lindsey A Torre, Emmy L Tran, Susanna L Trost, Diana Valencia, Jennifer L Wilkers, Luke Yip, Sarah Zohdy

Affiliations

¹ Centers for Disease Control and Prevention (CDC), Atlanta, GA.
² National Institutes of Health, Durham, NC.
³ CDC, Atlanta, GA.

PMID: 34496196
PMCID: PMC8451181
DOI: 10.1056/NEJMc2113891

Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion

Lauren H Zauche et al. N Engl J Med. 2021.

. 2021 Oct 14;385(16):1533-1535.

doi: 10.1056/NEJMc2113891. Epub 2021 Sep 8.

Collaborators

CDC v-safe Covid-19 Pregnancy Registry Team:
Amena Abbas, Amanda Akosa, Dayna S Alexander, Kathryn E Arnold, Jamal Bankhead, Tabatha Barber, Amy Blum, Ellen Boundy, Virginia B Bowen, Kailyn M Brooks, Cheryl Broussard, Tara Brown, Veronica K Burkel, Gyan Chandra, Karen Chang, Dena Cherry-Brown, Monica DiRienzo, Tuyen Do, Charise Fox, Julianne M Gee, Robbie Gray, Caitlin J Green, Jennifer Hamborsky, Anne M Hause, Jennifer Hegle, Obehi Ilenikhena, Jessly Joy, Ashley Judge, Alaya Koneru, Zanie Leroy, Birook Mekonnen, Anne Moorman, Pedro L Moro, John F Nahabedian 3rd, Morgan Nail, Andrea Neiman, Kimberly Newsome, Suzanne Newton, Keydra Phillips Oladapo, Nicole S Olgun, H Pamela Pagano, Lakshmi Panagiotakopoulos, Youngjoo Park, Corrine Parker, Kara Polen, Emmitt Rathore, Tom T Shimabukuro, Penelope Strid, Jennifer M Swanson, Ayzsa F Tannis, Naomi K Tepper, Letha Thomas, Lindsey A Torre, Emmy L Tran, Susanna L Trost, Diana Valencia, Jennifer L Wilkers, Luke Yip, Sarah Zohdy

Affiliations

¹ Centers for Disease Control and Prevention (CDC), Atlanta, GA.
² National Institutes of Health, Durham, NC.
³ CDC, Atlanta, GA.

PMID: 34496196
PMCID: PMC8451181
DOI: 10.1056/NEJMc2113891

No abstract available

PubMed Disclaimer

Figures

**Figure 1. Cumulative Risk of Spontaneous Abortion in the v-safe Covid-19 Vaccine Pregnancy Registry and in Two Historical Cohorts.**
Data from Mukherjee were presented as race-specific rates and are provided here for White women to maximize comparability with the v-safe pregnancy registry.

See this image and copyright information in PMC

Comment on

doi: 10.1056/NEJMc2113526

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References

1. Allotey J, Stallings E, Bonet M, et al. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ 2020;370:m3320-m3320. - PMC - PubMed
1. Mukherjee S, Velez Edwards DR, Baird DD, Savitz DA, Hartmann KE. Risk of miscarriage among black women and white women in a U.S. prospective cohort study. Am J Epidemiol 2013;177:1271-1278. - PMC - PubMed
1. Magnus MC, Wilcox AJ, Morken N-H, Weinberg CR, Håberg SE. Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study. BMJ 2019;364:l869-l869. - PMC - PubMed
1. Goldhaber MK, Fireman BH. The fetal life table revisited: spontaneous abortion rates in three Kaiser Permanente cohorts. Epidemiology 1991;2:33-39. - PubMed
1. Shimabukuro TT, Kim SY, Myers TR, et al. Preliminary findings of mRNA Covid-19 vaccine safety in pregnant persons. N Engl J Med 2021;384:2273-2282. - PMC - PubMed

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[1] Allotey J, Stallings E, Bonet M, et al. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ 2020;370:m3320-m3320. - PMC - PubMed

[2] Allotey J, Stallings E, Bonet M, et al. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ 2020;370:m3320-m3320. - PMC - PubMed

[3] Mukherjee S, Velez Edwards DR, Baird DD, Savitz DA, Hartmann KE. Risk of miscarriage among black women and white women in a U.S. prospective cohort study. Am J Epidemiol 2013;177:1271-1278. - PMC - PubMed

[4] Mukherjee S, Velez Edwards DR, Baird DD, Savitz DA, Hartmann KE. Risk of miscarriage among black women and white women in a U.S. prospective cohort study. Am J Epidemiol 2013;177:1271-1278. - PMC - PubMed

[5] Magnus MC, Wilcox AJ, Morken N-H, Weinberg CR, Håberg SE. Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study. BMJ 2019;364:l869-l869. - PMC - PubMed

[6] Magnus MC, Wilcox AJ, Morken N-H, Weinberg CR, Håberg SE. Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study. BMJ 2019;364:l869-l869. - PMC - PubMed

[7] Goldhaber MK, Fireman BH. The fetal life table revisited: spontaneous abortion rates in three Kaiser Permanente cohorts. Epidemiology 1991;2:33-39. - PubMed

[8] Goldhaber MK, Fireman BH. The fetal life table revisited: spontaneous abortion rates in three Kaiser Permanente cohorts. Epidemiology 1991;2:33-39. - PubMed

[9] Shimabukuro TT, Kim SY, Myers TR, et al. Preliminary findings of mRNA Covid-19 vaccine safety in pregnant persons. N Engl J Med 2021;384:2273-2282. - PMC - PubMed

[10] Shimabukuro TT, Kim SY, Myers TR, et al. Preliminary findings of mRNA Covid-19 vaccine safety in pregnant persons. N Engl J Med 2021;384:2273-2282. - PMC - PubMed

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Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion

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Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion

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