Exploring Sensory Subgroups in Typical Development and Autism Spectrum Development Using Factor Mixture Modelling

J Autism Dev Disord. 2022 Sep;52(9):3840-3860. doi: 10.1007/s10803-021-05256-6. Epub 2021 Sep 9.

Abstract

This study uses factor mixture modelling of the Short Sensory Profile (SSP) at two time points to describe subgroups of young autistic and typically-developing children. This approach allows separate SSP subscales to influence overall SSP performance differentially across subgroups. Three subgroups were described, one including almost all typically-developing participants plus many autistic participants. SSP performance of a second, largely-autistic subgroup was predominantly shaped by a subscale indexing behaviours of low energy/weakness. Finally, the third subgroup, again largely autistic, contained participants with low (or more "atypical") SSP scores across most subscales. In this subgroup, autistic participants exhibited large P1 amplitudes to loud sounds. Autistic participants in subgroups with more atypical SSP scores had higher anxiety and more sleep disturbances.

Keywords: Auditory P1; Auditory event-related potentials (ERPs); Autism; Factor mixture modelling; Heterogeneity; Sensory processing.

MeSH terms

  • Autism Spectrum Disorder*
  • Autistic Disorder*
  • Child
  • Child Development Disorders, Pervasive*
  • Humans