Advanced Endoscopic Techniques for the Diagnosis of Pancreatic Cancer and Management of Biliary and GastricOutlet Obstruction

Surg Oncol Clin N Am. 2021 Oct;30(4):639-656. doi: 10.1016/j.soc.2021.06.005. Epub 2021 Jul 22.

Abstract

Following high-quality imaging studies for staging, endoscopic ultrasound examination fine needle aspiration/biopsy is the preferred modality for tissue diagnosis of pancreatic cancer. Endoscopic retrograde cholangiopancreatography with metal stent placement is used for palliation of malignant biliary obstruction. Metal stents can be placed in patients with resectable pancreatic cancer in whom surgery is going to be delayed. For palliation of gastric outlet obstruction, endoscopic enteral stenting is often selected because of its less invasiveness. Endoscopic ultrasound-guided biliary drainage for malignant biliary obstruction or gastrojejunostomy for gastric outlet obstruction are emerging less invasive techniques as compared with palliative surgery.

Keywords: Endoscopic retrograde cholangiopancreatography; Endoscopic ultrasonography; Gastric outlet obstruction; Malignant biliary obstruction; Pancreatic cancer; Stents.

Publication types

  • Review

MeSH terms

  • Cholangiopancreatography, Endoscopic Retrograde
  • Cholestasis*
  • Endosonography
  • Gastric Outlet Obstruction* / diagnosis
  • Gastric Outlet Obstruction* / etiology
  • Gastric Outlet Obstruction* / surgery
  • Humans
  • Palliative Care
  • Pancreatic Neoplasms* / complications
  • Pancreatic Neoplasms* / diagnosis
  • Stents
  • Treatment Outcome