Stress exposure and well-being: correlates of meeting criteria for bipolar disorder, borderline personality disorder, or both

Soc Psychiatry Psychiatr Epidemiol. 2022 Sep;57(9):1885-1896. doi: 10.1007/s00127-021-02172-z. Epub 2021 Sep 15.

Abstract

Purpose: Bipolar and borderline personality disorders share similar features, are challenging to differentiate and sometimes co-occur in the same individual. This paper compares people with bipolar, borderline, both or neither, analyzing sociodemographic characteristics, lifetime exposure to stressors, and emotional, social, and physical wellbeing to illuminate differences in life experiences associated with expressing symptoms consistent with bipolar, borderline, or both.

Methods: Data were analyzed from the 2012-13 National Epidemiological Survey on Alcohol and Related Conditions (NESARC-III), N = 36,309. Survey participants were classified as bipolar (N = 488, 1.3%), borderline (N = 1758, 4.8%), both (N = 388, 1.1%), or neither (N = 33,675, 92.8%). Differences between these groups regarding demographics, adverse childhood experiences, recent stressors, lifetime trauma, psychiatric co-morbidities, and emotional, social, and physical wellbeing were assessed with the adjusted Wald F test.

Results: People with bipolar were more likely to also have borderline (44.3%) than the reverse (18.1%). People with both disorders were least advantaged socioeconomically, most exposed to stressors and traumas across the life course, and had the worst wellbeing emotionally, socially, and physically. Differences between people with both disorders vs. borderline only were smaller than between people with borderline vs. bipolar, although bipolar disorder was associated with considerable hardship relative to having neither disorder.

Conclusion: Borderline personality disorder alone or in combination with bipolar is associated with worse economic, social, and health outcomes than bipolar alone. Borderline can resolve with evidence-based treatment, and it is critical to correctly differentiate between the two conditions, so people with borderline and/or bipolar have the optimum chance for recovery.

Keywords: Adverse childhood experiences; Bipolar disorder; Borderline personality disorder; Psychiatric co-morbidity; Trauma; Wellbeing.

MeSH terms

  • Bipolar Disorder* / psychology
  • Borderline Personality Disorder* / diagnosis
  • Borderline Personality Disorder* / epidemiology
  • Borderline Personality Disorder* / psychology
  • Comorbidity
  • Diagnostic and Statistical Manual of Mental Disorders
  • Humans
  • Life Change Events