Intima-Media Thickness Measurements of the Common Carotid Artery in Patients with Central Serous Chorioretinopathy: A Case-Control Study

Kobra Nasrollahi; Amirhossein Farahi; Fatemeh Paknazar; Mohamadreza Akhlaghi; Farhad Fazel; Ehsan Zarepur; Mohsen Pourazizi

doi:10.1155/2021/6652373

Intima-Media Thickness Measurements of the Common Carotid Artery in Patients with Central Serous Chorioretinopathy: A Case-Control Study

J Ophthalmol. 2021 Sep 4:2021:6652373. doi: 10.1155/2021/6652373. eCollection 2021.

Authors

Kobra Nasrollahi¹, Amirhossein Farahi¹, Fatemeh Paknazar^{2

3}, Mohamadreza Akhlaghi¹, Farhad Fazel¹, Ehsan Zarepur⁴, Mohsen Pourazizi¹

Affiliations

¹ Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
² Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran.
³ Department of Epidemiology and Biostatistics, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
⁴ Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Purpose: To evaluate the intima-media thickness (IMT) of the left and right common carotid arteries (CCA) as an indicator of subclinical atherosclerosis in patients with central serous chorioretinopathy (CSCR).

Methods: This was a case-control study involving patients with CSCR and a matched healthy control group. The mean and difference of the left and right CCA IMT were determined and compared between the two groups using carotid duplex high-resolution B-mode ultrasound equipment.

Results: The study enrolled 32 CSCR patients (68.8% female, mean age 38.22 ± 5.42 years) and 32 controls (65.6% female, mean age 39.56 ± 5.33 years). The difference in common carotid IMT between the right and left sides was significantly greater in the CSCR group than in the control group (p < 0.001). Additionally, according to logistic regression analysis, patients with CSCR had a greater chance of having differences in IMT between the two sides when compared to the control group (OR: 1.29, 95% CI: 1.09-1.52).

Conclusion: Our findings indicated that in the CSCR group, the difference between the right and left sides of CCA IMT was significantly greater than in the control group.