Droplets take DNA by force

Nat Phys. 2021 Sep;17(9):981-982. doi: 10.1038/s41567-021-01286-0. Epub 2021 Jul 8.

Abstract

Single-molecule experiments can now quantify the surface forces that compete to package tethered DNA into a protein-rich condensate - providing much-needed mechanistic insight into the phase behaviour of the entangled genome in the nucleus.