Effect of Recorded Maternal Voice on Emergence Delirium in Children Under General Anesthesia: A Randomized Controlled Trial

J Nerv Ment Dis. 2021 Nov 1;209(11):814-819. doi: 10.1097/NMD.0000000000001433.

Abstract

To determine the effect of recorded maternal voice on emergence delirium (ED) in children under general anesthesia, a three-group randomized trial was conducted. A total of 102 children were randomly assigned to mother recording group (n = 34), stranger recording group (n = 34), and control group (n = 34). All subjects were assessed for ED with the Pediatric Anesthesia Emergence Delirium Scale; pain with the Face, Legs, Activity, Cry, and Consolability Scale; and various recovery durations and hemodynamic parameters at six time points. One-way analysis of variance showed that the ED score was significantly lower in the mother recording group (F = 18.520, p = 0.000), and statistical significance was observed in the duration of eye opening (p = 0.001) and tracheal extubation (p = 0.002). Generalized estimating equations observed interaction effects on heart rate and blood pressure (both p = 0.000). Mothers' voice might help reduce ED in children under general anesthesia.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Anesthesia, General*
  • Blood Pressure / physiology
  • Child
  • Child, Preschool
  • Double-Blind Method
  • Emergence Delirium / physiopathology*
  • Emergence Delirium / prevention & control*
  • Female
  • Heart Rate / physiology
  • Humans
  • Male
  • Mother-Child Relations*
  • Mothers
  • Outcome Assessment, Health Care
  • Speech Perception / physiology*
  • Voice