Eggerthella lenta bacteremia successfully treated with ceftizoxime: case report and review of the literature

Eur J Med Res. 2021 Sep 20;26(1):111. doi: 10.1186/s40001-021-00582-y.

Abstract

Eggerthella lenta is a normal human microflora that is anaerobic, non-sporulating, and Gram positive. However, an increasing number of studies have shown that it could also be an important pathogen for humans, even causing life-threatening infection under certain conditions. However, understanding its pathogenic mechanism and treatment options still need to be improved; more clinical data are needed to explore it further. In this article, we report a case of ceftizoxime-cured E. lenta bacteremia and review the recent literature to provide more clinical data for the diagnosis of E. lenta bacteremia. Our report suggests that the frequency of E. lenta bacteremia is increased in patients with hematologic or solid organ cancer, diabetes mellitus and also in those with appendicitis.

Keywords: Appendicitis; Bacteremia; Ceftizoxime; Eggerthella lenta.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Actinobacteria / isolation & purification
  • Actinobacteria / pathogenicity*
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Bacteremia / drug therapy*
  • Bacteremia / microbiology
  • Bacteremia / pathology
  • Ceftizoxime / therapeutic use*
  • Humans
  • Male
  • Prognosis

Substances

  • Anti-Bacterial Agents
  • Ceftizoxime

Supplementary concepts

  • Eggerthella lenta