Incidence of lymphogranuloma venereum increased in England during 2018-2019, after a period of decline. Our retrospective analysis of national surveillance data identified a rapid increase in diagnoses among HIV-negative men who have sex with men. These findings indicate a need for sustained surveillance and targeted public health action.
Keywords: Chlamydia trachomatis; England; HIV/AIDS; LGV; Lymphogranuloma venereum; epidemiology; infectious disease; men who have sex with men; sexually transmitted infections.