RNALocate v2.0: an updated resource for RNA subcellular localization with increased coverage and annotation

Nucleic Acids Res. 2022 Jan 7;50(D1):D333-D339. doi: 10.1093/nar/gkab825.

Abstract

Resolving the spatial distribution of the transcriptome at a subcellular level can increase our understanding of biology and diseases. To facilitate studies of biological functions and molecular mechanisms in the transcriptome, we updated RNALocate, a resource for RNA subcellular localization analysis that is freely accessible at http://www.rnalocate.org/ or http://www.rna-society.org/rnalocate/. Compared to RNALocate v1.0, the new features in version 2.0 include (i) expansion of the data sources and the coverage of species; (ii) incorporation and integration of RNA-seq datasets containing information about subcellular localization; (iii) addition and reorganization of RNA information (RNA subcellular localization conditions and descriptive figures for method, RNA homology information, RNA interaction and ncRNA disease information) and (iv) three additional prediction tools: DM3Loc, iLoc-lncRNA and iLoc-mRNA. Overall, RNALocate v2.0 provides a comprehensive RNA subcellular localization resource for researchers to deconvolute the highly complex architecture of the cell.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Cell Compartmentation
  • Databases, Nucleic Acid*
  • Datasets as Topic
  • Drosophila melanogaster / genetics
  • Drosophila melanogaster / metabolism
  • Eukaryotic Cells / cytology
  • Eukaryotic Cells / metabolism
  • Gene Expression Regulation
  • Gene Ontology
  • Humans
  • Internet
  • Mice
  • Molecular Sequence Annotation
  • RNA, Untranslated / classification
  • RNA, Untranslated / genetics*
  • RNA, Untranslated / metabolism
  • Rats
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism
  • Sequence Alignment
  • Sequence Homology, Nucleic Acid
  • Software*
  • Subcellular Fractions / chemistry
  • Subcellular Fractions / metabolism
  • Transcriptome*
  • Zebrafish / genetics
  • Zebrafish / metabolism

Substances

  • RNA, Untranslated