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Review
. 2021 Sep 23;15(9):e0009717.
doi: 10.1371/journal.pntd.0009717. eCollection 2021 Sep.

Blocking HTLV-1/2 silent transmission in Brazil: Current public health policies and proposal for additional strategies

Carolina Rosadas  1 , Maria Luiza B Menezes  2 , Bernardo Galvão-Castro  3 , Tatiane Assone  4 , Angélica E Miranda  5 , Mayra G Aragón  5 , Adele Caterino-de-Araujo  6 , Graham P Taylor  1 , Ricardo Ishak  7
Affiliations
Free PMC article
Review

Blocking HTLV-1/2 silent transmission in Brazil: Current public health policies and proposal for additional strategies

Carolina Rosadas et al. PLoS Negl Trop Dis. .
Free PMC article

Abstract

Human T-cell lymphotropic viruses 1 and 2 (HTLV-1/2) are relatively common in Brazil but remain silent and neglected infections. HTLV-1 is associated with a range of diseases with high morbidity and mortality. There is no curative treatment for this lifelong infection, so measures to prevent transmission are essential. This narrative review discusses HTLV-1/2 transmission routes and measures to prevent its continuous dissemination. The public health policies that are currently implemented in Brazil to avoid HTLV-1/2 transmission are addressed, and further strategies are proposed.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Flowchart proposal for management of HTLV-1/2 infection in pregnant women and prevention of mother-to-child transmission.
CMIA, chemiluminescence assay; HTLV-1/2, human T-cell lymphotropic virus 1 and 2; LIA, line immunoassay; WB, western blot.
See this image and copyright information in PMC

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