Segregation analyses and gene-centromere distances in zebrafish

Genetics. 1986 Feb;112(2):311-9.

Abstract

The gol-1, gol-2, alb-1 and spa-1 mutations affect pigment pattern in the zebrafish. We show here that these loci are unlinked to each other. In addition, gene-centromere distances were determined for these loci by analysis of half-tetrads obtained by the inhibition of the second meiotic division. The fractions of tetratype (second-division segregation) tetrads range from 0.24 (spa-1) to 0.89 (gol-1). The observation of greater than 0.67 second-division segregation indicates that the zebrafish has high chiasma interference.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Centromere*
  • Chromosomes*
  • Fishes / genetics*
  • Genetic Linkage*
  • Genetic Markers
  • Homozygote
  • Lod Score
  • Mutation
  • Pigmentation
  • Recombination, Genetic

Substances

  • Genetic Markers