Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant

Sriharsha Talluri; Michael A Goedde; Susan Coventry; Eran Rosenberg; Katie L Canalichio; Dennis Peppas; Jeffrey T White

doi:10.3389/fped.2021.729917

Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant

Front Pediatr. 2021 Sep 7:9:729917. doi: 10.3389/fped.2021.729917. eCollection 2021.

Authors

Sriharsha Talluri¹, Michael A Goedde¹, Susan Coventry², Eran Rosenberg^{1

3}, Katie L Canalichio^{1

3}, Dennis Peppas^{1

3}, Jeffrey T White^{1

3}

Affiliations

¹ Department of Urology, University of Louisville, Louisville, KY, United States.
² Department of Pediatric Anatomic Pathology, Norton Healthcare, Louisville, KY, United States.
³ Department of Pediatric Urology, Norton Healthcare, Louisville, KY, United States.

Abstract

The estimated incidence of pediatric testis tumor is 0.5-2.0 per 100,000 children, accounting for 1-2% of all pediatric tumors. Mixed germ cell tumors (MGCT) in prepubertal males are exceedingly rare, with only one previous case report found in the literature. We report a case of a MGCT in an infant. For prepubertal males, GCTs typically present with a painless scrotal mass, though trauma, testis torsion and hydrocele are also common presentations. Similar to such tumors in postpubertal males, ultrasonography, computed tomography, and tumor markers are integral to determine the best treatment. The patient described in this report presented with a painless scrotal mass. Following orchiectomy, the patient was found to have MGCT that was limited to the testis. With prudent management, these patients tend to have favorable prognoses.

Keywords: germ cell tumor; pediatric cancer; pediatric urology; surgery; testicular tumor.

Publication types

Case Reports