Coronary Artery Changes in Patients with Multisystem Inflammatory Syndrome in Children: Los Angeles Experience

J Pediatr. 2022 Jan:240:292-296. doi: 10.1016/j.jpeds.2021.09.026. Epub 2021 Sep 21.

Abstract

We compared cardiac findings in patients with multisystem inflammatory syndrome in children and Kawasaki disease in the first 6 months of the 2020 coronavirus disease pandemic to patients with Kawasaki disease during 2016-2019. We saw a high rate of coronary aneurysms in 2020, with a similar rate of coronary involvement but greater volume and incidence of cardiac dysfunction compared with previous years.

Keywords: Kawasaki disease; MIS-C; coronary aneurysm; echocardiogram.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • COVID-19 / blood
  • COVID-19 / complications*
  • COVID-19 / physiopathology*
  • Child
  • Child, Preschool
  • Coronary Aneurysm / complications
  • Coronary Aneurysm / physiopathology*
  • Coronary Vessels / physiopathology*
  • Echocardiography
  • Female
  • Humans
  • Immunoglobulin G
  • Infant
  • Los Angeles
  • Male
  • Mucocutaneous Lymph Node Syndrome / complications
  • Mucocutaneous Lymph Node Syndrome / physiopathology*
  • Systemic Inflammatory Response Syndrome / blood
  • Systemic Inflammatory Response Syndrome / complications
  • Systemic Inflammatory Response Syndrome / physiopathology*
  • Ventricular Dysfunction, Left / complications
  • Ventricular Dysfunction, Left / physiopathology

Substances

  • Immunoglobulin G

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related