Delivering the message: How a novel technology enabled the rapid development of effective vaccines

Lucy Shapiro; Richard Losick

doi:10.1016/j.cell.2021.08.019

Delivering the message: How a novel technology enabled the rapid development of effective vaccines

Cell. 2021 Oct 14;184(21):5271-5274. doi: 10.1016/j.cell.2021.08.019. Epub 2021 Sep 24.

Authors

Lucy Shapiro¹, Richard Losick²

Affiliations

¹ Department of Developmental Biology, Stanford School of Medicine, Stanford, CA, USA. Electronic address: shapiro@stanford.edu.
² Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA. Electronic address: losick@mcb.harvard.edu.

Abstract

This year's Lasker∼Debakey Clinical Research Award honors Katalin Karikó and Drew Weissman for the development of a therapeutic technology based on nucleoside-modification of messenger RNA, enabling the rapid development of the highly effective COVID-19 vaccines.

MeSH terms

Biotechnology / methods*
COVID-19 / epidemiology
COVID-19 / immunology
COVID-19 / prevention & control*
COVID-19 / virology
COVID-19 Vaccines / administration & dosage*
Humans
RNA, Messenger / administration & dosage*
RNA, Messenger / chemistry
SARS-CoV-2 / immunology*
Vaccines, Synthetic / administration & dosage*
mRNA Vaccines

Substances

COVID-19 Vaccines
RNA, Messenger
Vaccines, Synthetic