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. 2021 Oct;21(10):618-619.

doi: 10.1038/s41577-021-00601-3.

Metabolism as a driver of immunity

Erika L Pearce¹

Affiliations

PMID: 34580450
DOI: 10.1038/s41577-021-00601-3

Metabolism as a driver of immunity

Erika L Pearce. Nat Rev Immunol. 2021 Oct.

. 2021 Oct;21(10):618-619.

doi: 10.1038/s41577-021-00601-3.

Author

Erika L Pearce¹

Affiliation

¹ Johns Hopkins University, Baltimore, MD, USA. epearce6@jhmi.edu.

PMID: 34580450
DOI: 10.1038/s41577-021-00601-3

No abstract available

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References

Original articles

1. Frauwirth, K. A. et al. The CD28 signaling pathway regulates glucose metabolism. Immunity 16, 769–777 (2002) - DOI
1. Pearce, E. L. et al. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 460, 103–107 (2009) - DOI
1. Wang, R. et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 35, 871–882 (2011) - DOI
1. Michalek, R. D. et al. Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4⁺ T cell subsets. J. Immunol. 186, 3299–3303 (2011) - DOI
1. Krawczyk, C. M. et al. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood 115, 4742–4749 (2010) - DOI

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