COVID-view: Diagnosis of COVID-19 using Chest CT

IEEE Trans Vis Comput Graph. 2022 Jan;28(1):227-237. doi: 10.1109/TVCG.2021.3114851. Epub 2021 Dec 24.

Abstract

Significant work has been done towards deep learning (DL) models for automatic lung and lesion segmentation and classification of COVID-19 on chest CT data. However, comprehensive visualization systems focused on supporting the dual visual+DL diagnosis of COVID-19 are non-existent. We present COVID-view, a visualization application specially tailored for radiologists to diagnose COVID-19 from chest CT data. The system incorporates a complete pipeline of automatic lungs segmentation, localization/isolation of lung abnormalities, followed by visualization, visual and DL analysis, and measurement/quantification tools. Our system combines the traditional 2D workflow of radiologists with newer 2D and 3D visualization techniques with DL support for a more comprehensive diagnosis. COVID-view incorporates a novel DL model for classifying the patients into positive/negative COVID-19 cases, which acts as a reading aid for the radiologist using COVID-view and provides the attention heatmap as an explainable DL for the model output. We designed and evaluated COVID-view through suggestions, close feedback and conducting case studies of real-world patient data by expert radiologists who have substantial experience diagnosing chest CT scans for COVID-19, pulmonary embolism, and other forms of lung infections. We present requirements and task analysis for the diagnosis of COVID-19 that motivate our design choices and results in a practical system which is capable of handling real-world patient cases.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • COVID-19*
  • Computer Graphics
  • Humans
  • Lung / diagnostic imaging
  • SARS-CoV-2
  • Tomography, X-Ray Computed

Grants and funding

This work was funded in part by NSF grants CNS1650499, OAC1919752, ICER1940302, and IIS2107224, and OVPR-IEDM COVID-19 grant.