Patterns of mortality among commercial pressmen

J Natl Cancer Inst. 1986 Jun;76(6):1047-51.


A proportionate analysis of cause of death in 1,401 commercial pressmen was initiated following a report of a cancer cluster in this group. The study found a significant elevated risk of all cancers [proportionate mortality ratio (PMR) = 127] and cancers of the lymphatic and hematopoietic system (PMR = 122), with non-Hodgkin's lymphomas responsible for much of the excess. Three deaths in the cohort were attributed to myelofibrosis, a rare disease associated with benzene exposure. A significantly elevated PMR was also detected for colorectal cancer (PMR = 171) and, among those employed 20 years or more, for cancers of the liver (PMR = 216) and pancreas (PMR = 162). No excess risk of bladder or lung cancer or leukemia was seen. Proportionate mortality analyses rarely show excess risk of both cancer and heart disease in a working population. Surprisingly, a significantly elevated risk of arteriosclerotic heart disease (PMR = 113) was found in this group. These findings indicate that solvent exposure may be associated with excess mortality risk in commercial pressmen.

MeSH terms

  • Cardiovascular Diseases / mortality
  • Environmental Exposure
  • Humans
  • Intestinal Neoplasms / mortality
  • Leukemia / mortality
  • Liver Neoplasms / mortality
  • Mortality*
  • Neoplasms / mortality
  • New Jersey
  • New York
  • Occupational Diseases / mortality
  • Pancreatic Neoplasms / mortality
  • Printing*
  • Risk
  • Solvents
  • Urinary Bladder Neoplasms / mortality


  • Solvents