Rubella Eradication: Not Yet Accomplished, but Entirely Feasible

J Infect Dis. 2021 Sep 30;224(12 Suppl 2):S360-S366. doi: 10.1093/infdis/jiaa530.

Abstract

Rubella virus is the most teratogenic virus known to science and is capable of causing large epidemics. The RA 27/3 rubella vaccine, usually combined with measles vaccine, has eliminated rubella and congenital rubella syndrome from much of the world, notably from the Western Hemisphere. Except in immunosuppressed individuals, it is remarkably safe. Together with rubella vaccine strains used in China and Japan, eradication of the rubella virus is possible, indeed more feasible than eradication of measles or mumps.

Keywords: congenital; eradication; measles; rubella.

MeSH terms

  • Antibodies, Viral
  • Disease Eradication
  • Global Burden of Disease
  • Humans
  • Infant
  • Measles-Mumps-Rubella Vaccine*
  • Rubella / epidemiology
  • Rubella / prevention & control*
  • Rubella virus / immunology*

Substances

  • Antibodies, Viral
  • Measles-Mumps-Rubella Vaccine