Electrodiagnostic Assessment of Neuromuscular Junction Disorders

Neurol Clin. 2021 Nov;39(4):1051-1070. doi: 10.1016/j.ncl.2021.06.013. Epub 2021 Sep 3.

Abstract

Please verify edits, "These techniques", or specify. This article reviews advanced electrodiagnostic techniques used to assess for neuromuscular junction disorders, including repetitive nerve stimulation, conventional or concentric-needle single-fiber electromyography (SFEMG), and stimulated SFEMG. These techniques have high sensitivity but limited specificity. Novel methods currently under investigation are discussed, including vestibular ocular myogenic potential and oculography analysis.

Keywords: Myasthenia gravis; Neuromuscular junction; RNS; Repetitive nerve stimulation; SFEMG; Single-fiber electromyography.

Publication types

  • Review

MeSH terms

  • Electric Stimulation
  • Electromyography
  • Humans
  • Myasthenia Gravis*
  • Neurologic Examination
  • Neuromuscular Junction Diseases* / diagnosis