Factors Associated With Primary Nonresponsiveness to Antibiotics in Adults With Uncomplicated Acute Appendicitis: A Prespecified Secondary Analysis of a Randomized Clinical Trial

Jussi Haijanen; Suvi Sippola; Eliisa Löyttyniemi; Saija Hurme; Juha Grönroos; Tero Rautio; Paulina Salminen

doi:10.1001/jamasurg.2021.5003

Factors Associated With Primary Nonresponsiveness to Antibiotics in Adults With Uncomplicated Acute Appendicitis: A Prespecified Secondary Analysis of a Randomized Clinical Trial

JAMA Surg. 2021 Dec 1;156(12):1179-1181. doi: 10.1001/jamasurg.2021.5003.

Authors

Jussi Haijanen¹, Suvi Sippola¹, Eliisa Löyttyniemi², Saija Hurme², Juha Grönroos¹, Tero Rautio³, Paulina Salminen¹

Affiliations

¹ Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
² Department of Biostatistics, University of Turku, Turku, Finland.
³ Department of Surgery, Oulu University Hospital, Oulu, Finland.

Abstract

This secondary analysis of a randomized clinical trial assesses potential preintervention findings associated with primary nonresponsiveness to antibiotics in adults with uncomplicates acute appendicitis.

Publication types

Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Acute Disease
Administration, Intravenous
Administration, Oral
Adolescent
Adult
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / therapeutic use*
Appendicitis / drug therapy*
Female
Finland
Humans
Male
Middle Aged
Patient Selection
Treatment Failure*

Substances

Anti-Bacterial Agents