Conjunctivitis and other ocular findings in patients with COVID-19 infection

Ann Saudi Med. 2021 Sep-Oct;41(5):280-284. doi: 10.5144/0256-4947.2021.280. Epub 2021 Oct 7.

Abstract

Background: COVID-19 is an acute respiratory illness caused by a novel coronavirus (SARS-CoV-2). COVID-19 that might affect the eye in the form of conjunctivitis and other ocular features.

Objectives: Assess the frequency and clinical profile of conjunctivitis and other ocular findings in Iraqi patients with confirmed COVID-19 infection.

Design: Analytical cross-sectional study.

Setting: Secondary care center.

Patients and methods: This study involved patients diagnosed with SARS-CoV-2 viral infection of variable disease severity from June 2020 to December 2020. Ocular history and the severity of SARS-CoV-2 viral infection was assessed for all of the patients.

Main outcome measures: Frequency of conjunctival inflammation and other ocular findings in patients with coronavirus infection.

Sample size: 186 patients.

Results: The patients had a mean (standard deviation, range) age of 44.4 (18.8, 18-78) years. Conjunctivitis was present in 25 patients (13.4%). There was no significant association between prevalence of conjunctivitis and patient gender (P=.868). However, conjunctivitis was significantly associated with the severity of the disease (P=.018): the rate of conjunctivitis was significantly higher in cases with severe disease (28%) in comparison with those with mild to moderate clinical presentation (9.3%). The natural course of conjunctivitis seemed to be mild with no effect on visual acuity and no short-term complications.

Conclusion: Conjunctivitis can occur in patients with SARS-CoV-2 viral infection, and could be a presenting sign. Conjunctivitis is more common in cases of severe COVID-19 infection and since it could be a presenting sign it might be of benefit in the early diagnosis and treatment of COVID-19.

Limitation: Single-center study, safety limitations in the examination of the patients.

Conflict of interest: None.

MeSH terms

  • Adult
  • Aged
  • COVID-19*
  • Conjunctivitis* / epidemiology
  • Conjunctivitis* / etiology
  • Cross-Sectional Studies
  • Humans
  • Middle Aged
  • SARS-CoV-2

Grants and funding

None