Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021

Euro Surveill. 2021 Oct;26(40):2100921. doi: 10.2807/1560-7917.ES.2021.26.40.2100921.

Abstract

We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.

Keywords: COVID-19; Delta variant; Public health response; RT-PCR; SARS-CoV-2; VOC.

MeSH terms

  • COVID-19* / epidemiology
  • COVID-19* / virology
  • Genomics
  • Humans
  • Netherlands / epidemiology
  • Polymerase Chain Reaction
  • RNA, Viral / genetics
  • SARS-CoV-2* / genetics

Substances

  • RNA, Viral