Gene drive: a faster route to plant improvement

Hamid Anees Siddiqui; Tim Harvey-Samuel; Shahid Mansoor

doi:10.1016/j.tplants.2021.09.005

Gene drive: a faster route to plant improvement

Trends Plant Sci. 2021 Dec;26(12):1204-1206. doi: 10.1016/j.tplants.2021.09.005. Epub 2021 Oct 6.

Authors

Hamid Anees Siddiqui¹, Tim Harvey-Samuel², Shahid Mansoor³

Affiliations

¹ Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, a constituent College of Pakistan Institute of Engineering and Applied Sciences, Faisalabad, Pakistan.
² Arthropod Genetics Group, The Pirbright Institute, Woking, UK.
³ Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, a constituent College of Pakistan Institute of Engineering and Applied Sciences, Faisalabad, Pakistan. Electronic address: shahidmansoor7@gmail.com.

PMID: 34625344
DOI: 10.1016/j.tplants.2021.09.005

Abstract

Gene drives for control of vector-borne diseases have been demonstrated in insects but remain challenging in plants. Theoretically, they could be transformative in speeding breeding programs and contributing to food security through providing novel weed control methods. Zhang et al. now report the possibility of implementing gene drive in plants for the first time.

Keywords: CRISPR/Cas9; NPBTs; gene drive; genome editing, HDR; weeds.

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MeSH terms

CRISPR-Cas Systems
Gene Drive Technology*
Gene Editing
Plant Breeding
Plants / genetics