Fasciculations in Children

Pediatr Neurol. 2021 Dec;125:40-47. doi: 10.1016/j.pediatrneurol.2021.08.008. Epub 2021 Sep 6.


Fasciculations are the most common form of spontaneous muscle contraction. They frequently occur in healthy individuals. However, there are a minority of situations that fasciculations are observed in association with specific neurologic disorders. Publications concerning the evaluation of pediatric patients experiencing fasciculations are limited. These children may undergo invasive or expensive diagnostic investigations that are unnecessary. Moreover, without careful consideration of differential diagnoses, rare neuromuscular disorders that present with fasciculations in the pediatric age group can be under-recognized by pediatric neurologists. This review examines the most important pediatric disorders presenting with fasciculations and other spontaneous muscle contractions to guide pediatric neurologists in evaluating these children.

Keywords: Children; Fasciculations; Myokymia; Neuromyotonia; Spontaneous muscle contraction.

Publication types

  • Review

MeSH terms

  • Child
  • Fasciculation / diagnosis*
  • Fasciculation / etiology
  • Humans
  • Neuromuscular Diseases / complications
  • Neuromuscular Diseases / diagnosis*