Radioembolization of Intrahepatic Cholangiocarcinoma: Patient Selection, Outcomes, and Competing Therapies

Semin Intervent Radiol. 2021 Oct;38(4):438-444. doi: 10.1055/s-0041-1735526. Epub 2021 Oct 7.

Abstract

Intrahepatic cholangiocarcinoma is the second most common primary hepatic malignancy and poses a therapeutic challenge owing to its late-stage presentation and treatment-resistant outcomes. Most patients are diagnosed with locally advanced, unresectable disease and are treated with a combination of systemic and local regional therapies. Transarterial radioembolization offers a survival benefit and a favorable side effect profile, with a growing body of evidence to support its use. Herein, we review patient selection and detail outcomes of radioembolization for intrahepatic cholangiocarcinoma, together with mention of competing treatments.

Keywords: interventional radiology; intrahepatic cholangiocarcinoma; local regional therapy; radioembolization; yttrium-90.

Publication types

  • Review