Pancreatic Cancer Survival Prediction: A Survey of the State-of-the-Art

Comput Math Methods Med. 2021 Sep 30:2021:1188414. doi: 10.1155/2021/1188414. eCollection 2021.

Abstract

Cancer early detection increases the chances of survival. Some cancer types, like pancreatic cancer, are challenging to diagnose or detect early, and the stages have a fast progression rate. This paper presents the state-of-the-art techniques used in cancer survival prediction, suggesting how these techniques can be implemented in predicting the overall survival of pancreatic ductal adenocarcinoma cancer (pdac) patients. Because of bewildering and high volumes of data, the recent studies highlight the importance of machine learning (ML) algorithms like support vector machines and convolutional neural networks. Studies predict pancreatic ductal adenocarcinoma cancer (pdac) survival is within the limits of 41.7% at one year, 8.7% at three years, and 1.9% at five years. There is no significant correlation found between the disease stages and the overall survival rate. The implementation of ML algorithms can improve our understanding of cancer progression. ML methods need an appropriate level of validation to be considered in everyday clinical practice. The objective of these techniques is to perform classification, prediction, and estimation. Accurate predictions give pathologists information on the patient's state, surgical treatment to be done, optimal use of resources, individualized therapy, drugs to prescribe, and better patient management.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Carcinoma, Pancreatic Ductal / diagnostic imaging*
  • Carcinoma, Pancreatic Ductal / mortality*
  • Computational Biology
  • Deep Learning
  • Early Detection of Cancer
  • Humans
  • Machine Learning*
  • Neural Networks, Computer
  • Pancreatic Neoplasms / diagnostic imaging*
  • Pancreatic Neoplasms / mortality*
  • Prognosis
  • Support Vector Machine
  • Surveys and Questionnaires
  • Survival Analysis
  • Survival Rate